How Magic Mushrooms Affect Your Brain


Narrator: This is the map
of a typical human brain, and this is the map of
a brain on psilocybin, the psychoactive compound
in magic mushrooms. All those new connections you can see don’t just make people trip. They’re also the reason that psilocybin is one of today’s most talked-about drugs in certain medical circles. Worldwide, more than
180 species of mushrooms produce psilocybin, likely
as a defense strategy. Scientists believe that psilocybin may dampen the appetite of
predatory insects like ants so that they feel full long
before eating their way through the entire mushroom. Humans, on the other
hand, well, they trip. Johnson: Psilocybin is a
so-called classic psychedelic, so it’s in the same
category as drugs like LSD and works in the brain in
basically the same way. Narrator: When you take
psilocybin, your gut converts it into another chemical, known as psilocin, which binds to serotonin
receptors called 2A, and experts think that’s what triggers what they call neuronal avalanching. It’s essentially a domino effect of different changes in the brain. You’ve got increased activity
in the visual cortex, which leads to changes in your perception, and then decreased network activity in the default mode network,
which leads to a loss of ego. Johnson: And that may be
why people often report at high doses a profound sense of unity,
transcending beyond themselves. Narrator: But perhaps most importantly, psilocybin increases connectivity among different regions of the brain. Johnson: Because of that
receptor activation, there is a profound change in the way that different
areas of the brain synchronize with each other. Narrator: Think of it like an orchestra. Normally, the brain has
different musical groups that each play independently. Johnson: A sextet there,
here’s a quartet there. This one’s playing jazz.
This one’s classical, and a number of other ones. Narrator: But once psilocybin enters, it’s like you suddenly have a conductor. Johnson: So there is this
communication between areas that are normally kind
of compartmentalized and doing their own thing. Narrator: Scientists believe
that it’s a combination of these effects that
make psilocybin so useful for combating depression and addiction. When new areas in the brain
start talking to each other, for example, you might have
new insights into old problems. And that’s why some
experts describe tripping as a condensed version of talk therapy. And then dissolving your
ego, Johnson says… Johnson: Can be profoundly healing. Narrator: And there’s
actually an increasing amount of research to prove it. In two studies published in 2016, researchers gave cancer
patients with depression a large dose of psilocybin,
and even six months later, at least 80% of them showed
significant decreases in depressed mood. And research on addiction
is equally promising. In a study led by Johnson,
15 volunteers took psilocybin to quit smoking, and after six months, 80% of them had kicked the habit, compared to a rate of about 35% for the drug varenicline,
which is widely considered the best smoking-cessation drug out there. Yet despite these results, psilocybin is still listed
as a Schedule I drug, a category reserved for compounds that have no currently
accepted medical use and a high potential for abuse. Now, taking magic mushrooms recreationally does come with some risks. Johnson: So a dramatic example would be driving under the influence of psilocybin or using it in a way that
interferes with your job, or your family relations, or
your schoolwork, for example. Narrator: But as far as scientists know, long-term use doesn’t damage the brain in the way that other drugs can, and according to at least one study, it’s actually the safest drug out there. In 2018, for example, just 0.3% of people who reported taking them needed
medical emergency treatment, compared to 0.9% for ecstasy
and 1.3% for alcohol. Taken altogether, that’s why some states across the country have campaigned to decriminalize psilocybin,
including Denver, which, in May of 2019, became
the first ever to succeed.

100 thoughts on “How Magic Mushrooms Affect Your Brain

  1. This is not cool, first weed is damaging and stoning people out , that's why everyone is emotionally detached these days, they are acting like a brain dead zombie,

    Magic mushrooms will add this epidemic to more worse than this chaos is,

    No one will have relationships in life anymore.

  2. Safest drug you sing well I don't have a life all I do is play in a rock band and sit on my ass all day so I think I'm going to buy some🤔🤔🤔🤔🤔🤔🤔

  3. Before commenting that the red & white mushroom aren’t magic read all the other 500 comments saying the same thing. Shit ppl.

  4. And here in the philippines my psychiatrist told me that he was called by the police because a teenager eat a psychedelic mushroom and became crazy.

  5. I had a friend taking 5 grams for the first time. 15 minutes after taking it He fell almost unconscious for about 4 hours. He cried, screamed, and was very sad shaking violently, and so on. But He is still depressed. Kinda of disappointment.

  6. Well I would have shared this if you did put mushrooms up what arnt magic.
    Even agaric is dangerous if not prepared properly 🍄
    👆🏻

  7. This is one of the worst videos on psilocybin I have ever seen. You show mushrooms constantly that are not species that have that compound and even showed amanita muscaria which can make you violently ill and is used to kill flies. Misidentification of mushroom is dangerous. There are look alikes that are deadly.

  8. Once I stuffed 75 grams of undried golden teachers down my hatch raw dog with my buddy who ate 83 grams and went on a journey in his mind and threw up. I just watched him trip cause I downed 70 grams two weeks before that and tripped and then went to sleep. My 2nd trip was nothing to me. They effect is diminished the more you take them cause you can only reset the brain so many times. It's been a few years though. Time for a modetrip.

  9. For a science channel, I find it highly irresponsible for you to (probably) deliberately show the wrong mushrooms in the video.

    Your fear of somebody dying from eating the wrong type should be greater than your (probable) concern that someone might try psychedelics because of you're video.

  10. That red mushroom in the intro is NOT a psilocybin containing mushroom!! Do not eat those raw… They are Amanita Muscaria…

  11. My friend just some shrooms, and invited me over this weekend to partake. Very much looking forward to the exsprience. It's been a year since I've had any. We will be ordetng pizza . With our own mushrooms. 😀

  12. I wrote this book and made this promo for people to see the good and bad times on Psychedelics
    https://www.youtube.com/playlist?list=PLDgg2OeZxHHsd1kf048geJ77h3K7KnQbd

  13. i'm from oman please if anyone from my country or other gulf countries is interested in dmt , magic mushroom and ayahuasca follow me on instagram : @albalushi_starseed

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  15. A very long time ago when i was young & dumb lol. My roomate at that time decided we needed to try one of the "magic mushrooms" well i sure did go an a magic trip& i was seeing giant purlpe 🐔 & little men going into my drink! Then coming back from my trip panic attacks set in. I was so 😡 at myself because she talked me into it. We smoked weed from time to time& her friend told her it has the same effects. Well no it dont. I was on an acid type trip. Never did that but, its the only way i can describe that crap. Never did that again! I tell my 2 girls dont you ever eat a magic shroom& tell them about the giant purple 🐔 & they cracked up 😆. I said its funny now but, dont you EVER!

  16. I only came here to say you should have used psilocybin mushrooms (for your thumbnail) which are safe instead of amanitas which can be deadly. Do some better research next time

  17. There is no psilocybin in fly agaric, the first red and white spotted mushroom first shown on this video
    The flys contain muscimol which has a more euphoric effect along with Micropsia and it’s opposite macropsia where objects seen smaller or larger than they really are. It’s the condition that inspiration Lewis Caroll when he wrote through the looking glass off his Barnet on these shrooms.

  18. Please don’t show Amanita muscaria when talking about psilocybes. Fairly certain this video also showed some deadly poisonous mushrooms as well in the lineup. People are very ignorant sometimes and will take anything without doing proper research. Taking the wrong mushrooms can result in needing a new liver.

  19. The none Psilocybin Mushrooms that are shown aside, Well Duh, let's really look into this, make it legal so real scientists can research it without being arrested. It has obvious benefits and only money hungry Pharma corps would want to hold it back. I think I explained my own doubts.

  20. A warning – DO NOT consume the white dotted red mushroom (Amanita Muscaria) or basically any shroomie in this without prior research – the majority of these are not even psilocybin mushrooms and could potentially be very dangerous.

  21. Hey adult kids the red mushrooms with the white are highly poisonous. Please before eating any mushrooms make sure they won't kill you.

  22. SO THIS IS WHY MARIO'S FIRST NAME IS SUPER….. THE WHOLE VIDEO GAME IS ABOUT HIM TRIPPING ON THE AMANITA MUSCARIA MUSHROOMS AND HALLUCINATING ADVENTURES OF STEPPING ON TURTLES IN A FOREST AND RIDING AN IGUANA HE CALLS YOSHI…. MARIO WAS A DOCTOR BEFORE HE DISCOVERED MUSHROOMS, BECAUSE HE GOT HIGH IN THE HOSPITAL, HE GOT FIRED AND THEN BECAME A PLUMBER. DRUGS ONLY MAKE YOUR LIFE GO DOWN AND WHY SO MANY PEOPLE ARE LAZY HOMELESS HOBOS THAT DON'T GET A CHANCE AT OTHER JOBS. DON'T ABUSE DRUGS; USE DRUGS WISELY.

  23. In the thumbnail there is an amanita muscaria other psychedelic mushrooms but not psycylobine
    Amanita Muscaria are harder to digest and they are much stronger

  24. If you are really interested in mushrooms, search Paul Stamets on YouTube. He is a master educator and relevant story teller. Go to his website and you will see someone with a long list of professional accolades. He is a real Mycologist and has been taking psilocybn since the late 60's.

  25. I have had a traumatic brain injury 5 years ago "TBI" I wonder if it is safe to take this after what happened to me.

  26. for the people wondering what the dose was in the study at 2:48 I calculated it to be equivalent to roughly 3 g of dried psilocybe cubensis, which is a hell of a trip.

  27. I hate these type of videos I have talked many drugs in. My life mushrooms and lsd too not recomending it.. At least lsd was too much for me.. Yeah u can try it and you not die but not recomending some experience are terrific

  28. You don’t want to go to work or drive while drinking alcohol or taking OxyContin either. Mushrooms are no different. So making this argument to keep them as a schedule 1 drug is asinine.

  29. WARNING THE AMANITA MUSCARIA MUSHROOM ( RED CAP WITH WHITE SPOTS) IS NOT A PSILOSYBIN MUSHROOM AND CAN BE FATAL IF TAKEN IRRISPONSABLY

  30. STOP USING AMINITA MUSCARIA THE PICTURE FOR PSILOCYBIN MUSHROOMS!!!!! LOST ALL CREDIBILITY ON THE THUMBNAIL…. jfc.

  31. I don't know anything about mushrooms but even I knew that red one with spots is poisonous. Most people are smart enough to not pick and eat mushrooms they know nothing about but some would.

  32. I know (501)904-9184 to be the only legit and trustworthy plug. I ordered mushroom from him last week and it was delivered to me

  33. THERE ARE GREAT,BUT TO BE ON IT ALL THE TIME IS INSANE!!!BALANCE THE SIN!!!🤘🤘🤘🙂🙂🙂!!!

  34. Amanita muscaria DOESN'T contain psilocybin!!!
    Don't use this video for educational purpouses… Go somwhere else please!

  35. I take prescription for anxiety and dont smoke weed much because that gave me anxiety (heart pumping and thought i was gonna have a heart attack) should i try shrooms? 🤔

  36. Yeah Interfere with work in your family life Like alcohol, Which is already legal I would take to trippin over alcohol any day

  37. Funky Shroom dress! https://www.etsy.com/listing/773247664/womens-skater-dressskater-dress?ref=shop_home_active_1&frs=1

  38. before the video I got an ad about how cannabis and mushrooms are the future and that its wrong that they are illegal because there plants from nature and a gift from mother nature. I-

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